🐞 Gene Mutation

The Cause of Mutations

Mutations are a random occurrence during DNA replication and the rate of mutation is influenced by external factors such as UV radiation. There are different types of mutation:

 

1. Deletion where a nucleotide base is deleted. AGTCA becomes AGCA.

2. Substitution where a nucleotide base is replaced by another. AGTCA becomes AGTCG.

3. Insertion where a nucleotide base is added as extra. AGTCA becomes ATGTCA.

 



The Effect of Mutations

Since the genetic code is degenerate, it’s possible that a mutation won’t have any effect whatsoever! This represents silent mutations. If 2 different triplet codes translate into the same amino acid, the polypeptide chain will remain unchanged. This of course only applies to…