Many chemicals can interfere withnervous transmission in a variety of different ways. We’ll be looking at the effects of nicotine found in tobacco, lidocaine used as an anaesthetic, and cobra venom transmitted via bites.
Nicotine
Nicotine is absorbed in thelungs and travels throughbloodto thebrain, where it behaves as acetylcholine, resulting in binding to its respective receptors. This results in a stimulant effect which is the cause of its high addictive potential. Symptoms can be highly subjective, but usually fall under relaxation, sharpness and calmness.
Lidocaine
Lidocaine can be applied topically to the skin via a patch or cream, as well as injected. It can numb specific areas and acts as a painkiller, hence is used as an anaesthetic in surgery, dental work, etc. It works by blocking voltage-gated Na+ ion channels, hence preventing the depolarisation of thepost-synaptic neurone. No pain signals can be transmitted to the brain because no signals are…
