All UK Exam Boards included

Gene Therapy

This is a legacy topic. View the most up to date content by selecting the exam board in the dropdown to the left.

 

Gene therapy involves inserting a functional gene into a patient who lacks it, or needs supplementary support. This works for conditions which are caused by a single faulty gene rather than multiple genes. The vector used to deliver the gene is a harmless virus. Once the new DNA is taken up in the cell nucleus, the gene is expressed like any other gene.

 

 

One problem associated with gene therapy is the immune reaction the body has to the virus. This may cause inflammation and other potentially serious side effects. Another issue is that of maintaining the effects of the healthy gene inserted into target cells. If these are recycled quickly or don’t pass on the new gene to their offspring cells, then the therapeutic effect stops there, and the case is that multiple rounds of gene therapy must be administered.

 

Conditions currently treated with gene therapy include: cystic fibrosis, haemophilia, Parkinson’s disease, muscular dystrophy, sickle cell anaemia among many others. One particular drug in gene therapy, Glybera, is famous for being the most expensive drug in the world at $1.6 million

Sorry! There are no posts.

Sorry! There are no posts.

Your Reviews

Just a huge thank you for spending your time helping others. I love your site and I'm seriously very grateful. No word of a lie

Neuron13 The Student Room

I got A* in A-level biology (Cambridge), thanks! I love your videos

Sherif Negm Facebook

OMG that’s great! Actually just helped me with my homework

mabelbarc The Student Room

Good topic notes and cool videos. I'll definitely recommend it to my students.

Seema Sehgal AQA Examiner and biology teacher on LinkedIn

OMG them videos are great! You're a goldmine - and I'm a gold digger ;)

sc12 YouTube